The deaths have cast a shadow over the school community and left the affected families and relatives mourning the young pupils.
The pupils, all aged between nine and 11, reportedly died on Tuesday, November 10, 2026, under circumstances that police are investigating to establish the exact cause of death.
According to preliminary police findings, the incident occurred at about 2:00pm in Kikulu Zone, Kikaaya Parish, Kawempe Division.
Three of the pupils reportedly died at their respective homes, while the fourth died at Kasangati Hospital, where she had been taken for medical attention.
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The deceased have been identified as Nakitende Mariam, 11, a Primary Four pupil; Kiruta Rwahim, 11, a Primary Five pupil; Nasuna Nusufa, 11, also in Primary Four; and Nabeta Failuzi, nine, a Primary Three pupil.
Police said postmortem examinations would be conducted to establish the exact cause of death and provide further medical findings.
Investigators are working to establish the circumstances under which the children died and whether poisoning was involved.
Police at Jinja Road Division said investigations were ongoing, adding that further details would be communicated as more information becomes available.
The deaths have cast a shadow over the school community and left the affected families and relatives mourning the young pupils.
The suspected poisoning has not yet been medically confirmed, pending the outcome of postmortem examinations and investigations.